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Identification of Key Signaling Pathways Orchestrating Substrate Topography Directed Osteogenic Differentiation Through High-Throughput siRNA Screening

Fibrous scaffolds are used for bone tissue engineering purposes with great success across a variety of polymers with different physical and chemical properties. It is now evident that the correct degree of curvature promotes increased cytoskeletal tension on osteoprogenitors leading to osteogenic di...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Ozdemir, Tugba, Bowers, Daniel T., Zhan, Xiang, Ghosh, Debashis, Brown, Justin L.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
Предметы:
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353928/
https://ncbi.nlm.nih.gov/pubmed/30700820
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37554-y
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