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Interaction of rs316019 variants of SLC22A2 with metformin and other drugs- an in silico analysis
Metformin is one of the first-line and most widely prescribed drugs to treat type 2 diabetes (T2D). Its clearance from circulation is mostly facilitated by SLC22A2 (OCT2) in the renal cells. SLC22A2 is a polyspecific organic cation transporter and mediate transport of structurally unrelated endogeno...
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| Publicado no: | J Genet Eng Biotechnol |
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| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Academy of Scientific Research and Technology, Egypt
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6353654/ https://ncbi.nlm.nih.gov/pubmed/30733798 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgeb.2018.01.003 |
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