Interaction of rs316019 variants of SLC22A2 with metformin and other drugs- an in silico analysis

Metformin is one of the first-line and most widely prescribed drugs to treat type 2 diabetes (T2D). Its clearance from circulation is mostly facilitated by SLC22A2 (OCT2) in the renal cells. SLC22A2 is a polyspecific organic cation transporter and mediate transport of structurally unrelated endogeno...

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Библиографические подробности
Опубликовано в: :J Genet Eng Biotechnol
Главные авторы: Sajib, Abu Ashfaqur, Islam, Tasmia, Paul, Nilanjana, Yeasmin, Sabina
Формат: Artigo
Язык:Inglês
Опубликовано: Academy of Scientific Research and Technology, Egypt 2018
Предметы:
In Silico Biotechnology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353654/
https://ncbi.nlm.nih.gov/pubmed/30733798
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jgeb.2018.01.003
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