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IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation
IKBKE (IKKε) has emerged as a key modulator of multiple substrates, controlling oncogenic pathways in various malignancies. mTOR signaling, required for cellular growth, proliferation, and vascular angiogenesis in cancer, is potentially one of the pathways regulated by IKKε. Upon activation by vario...
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| 出版年: | Turk J Biol |
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| 第一著者: | |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
The Scientific and Technological Research Council of Turkey
2018
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| 主題: | |
| オンライン・アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6353275/ https://ncbi.nlm.nih.gov/pubmed/30814890 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/biy-1801-57 |
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