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IKBKE inhibits TSC1 to activate the mTOR/S6K pathway for oncogenic transformation

IKBKE (IKKε) has emerged as a key modulator of multiple substrates, controlling oncogenic pathways in various malignancies. mTOR signaling, required for cellular growth, proliferation, and vascular angiogenesis in cancer, is potentially one of the pathways regulated by IKKε. Upon activation by vario...

詳細記述

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書誌詳細
出版年:Turk J Biol
第一著者: GÖKTUNA, Serkan İsmail
フォーマット: Artigo
言語:Inglês
出版事項: The Scientific and Technological Research Council of Turkey 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353275/
https://ncbi.nlm.nih.gov/pubmed/30814890
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3906/biy-1801-57
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