Toll-like Receptor 3 Is a Therapeutic Target for Pulmonary Hypertension

Rationale: Pulmonary arterial hypertension (PAH) is characterized by vascular cell proliferation and endothelial cell apoptosis. TLR3 (Toll-like receptor 3) is a receptor for double-stranded RNA and has been recently implicated in vascular protection. Objectives: To study the expression and role of...

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Publicado en:Am J Respir Crit Care Med
Main Authors: Farkas, Daniela, Thompson, A. A. Roger, Bhagwani, Aneel R., Hultman, Schuyler, Ji, Hyun, Kotha, Naveen, Farr, Grant, Arnold, Nadine D., Braithwaite, Adam, Casbolt, Helen, Cole, Jennifer E., Sabroe, Ian, Monaco, Claudia, Cool, Carlyne D., Goncharova, Elena A., Lawrie, Allan, Farkas, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado: American Thoracic Society 2019
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Original Articles
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6353001/
https://ncbi.nlm.nih.gov/pubmed/30211629
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1164/rccm.201707-1370OC
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