Clonally selected primitive endothelial cells promote occlusive pulmonary arteriopathy and severe pulmonary hypertension in rats exposed to chronic hypoxia

One current concept suggests that unchecked proliferation of clonally selected precursors of endothelial cells (ECs) contribute to severe pulmonary arterial hypertension (PAH). We hypothesized that clonally selected ECs expressing the progenitor marker CD117 promote severe occlusive pulmonary hypert...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Bhagwani, Aneel R., Farkas, Daniela, Harmon, Brennan, Authelet, Kayla J., Cool, Carlyne D., Kolb, Martin, Goncharova, Elena, Yoder, Mervin C., Clauss, Matthias, Freishtat, Robert, Farkas, Laszlo
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2020
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6981224/
https://ncbi.nlm.nih.gov/pubmed/31980720
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-020-58083-7
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