Nuclear Factor κB Inhibition Reduces Lung Vascular Lumen Obliteration in Severe Pulmonary Hypertension in Rats

NF-κB and IL-6, a NF-κB downstream mediator, play a central role in the inflammatory response of tissues. We aimed to determine the role of the classical NF-κB pathway in severe pulmonary arterial hypertension (PAH) induced by SU5416 and chronic hypoxia (SuHx) in rats. Tissue samples from patients w...

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Bibliografiske detaljer
Main Authors: Farkas, Daniela, Alhussaini, Aysar A., Kraskauskas, Donatas, Kraskauskiene, Vita, Cool, Carlyne D., Nicolls, Mark R., Natarajan, Ramesh, Farkas, Laszlo
Format: Artigo
Sprog:Inglês
Udgivet: American Thoracic Society 2014
Fag:
Original Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4189489/
https://ncbi.nlm.nih.gov/pubmed/24684441
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1165/rcmb.2013-0355OC
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