The functional consequences of sodium channel Na(V)1.8 in human left ventricular hypertrophy

AIMS: In hypertrophy and heart failure, the proarrhythmic persistent Na(+) current (I(NaL)) is enhanced. We aimed to investigate the electrophysiological role of neuronal sodium channel Na(V)1.8 in human hypertrophied myocardium. METHODS AND RESULTS: Myocardial tissue of 24 patients suffering from s...

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Pubblicato in:ESC Heart Fail
Autori principali: Ahmad, Shakil, Tirilomis, Petros, Pabel, Steffen, Dybkova, Nataliya, Hartmann, Nico, Molina, Cristina E., Tirilomis, Theodoros, Kutschka, Ingo, Frey, Norbert, Maier, Lars S., Hasenfuss, Gerd, Streckfuss‐Bömeke, Katrin, Sossalla, Samuel
Natura: Artigo
Lingua:Inglês
Pubblicazione: John Wiley and Sons Inc. 2018
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Original Research Articles
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6352890/
https://ncbi.nlm.nih.gov/pubmed/30378291
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/ehf2.12378
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