Lymph nodes as barriers to T‐cell rejuvenation in aging mice and nonhuman primates

In youth, thymic involution curtails production of new naïve T cells, placing the onus of T‐cell maintenance upon secondary lymphoid organs (SLO). This peripheral maintenance preserves the size of the T‐cell pool for much of the lifespan, but wanes in the last third of life, leading to a dearth of n...

詳細記述

保存先:
書誌詳細
出版年:Aging Cell
主要な著者: Thompson, Heather L., Smithey, Megan J., Uhrlaub, Jennifer L., Jeftić, Ilija, Jergović, Mladen, White, Sarah E., Currier, Noreen, Lang, Anna M., Okoye, Afam, Park, Byung, Picker, Louis J., Surh, Charles D., Nikolich‐Žugich, Janko
フォーマット: Artigo
言語:Inglês
出版事項: John Wiley and Sons Inc. 2018
主題:
Original Papers
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351843/
https://ncbi.nlm.nih.gov/pubmed/30430748
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/acel.12865
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