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Identification and Verification of Ubiquitin-Activated Bacterial Phospholipases
ExoU is a potent type III secretion system effector that is injected directly into mammalian cells by the opportunistic pathogen Pseudomonas aeruginosa. As a ubiquitin-activated phospholipase A(2) (PLA(2)), ExoU exhibits cytotoxicity by cleaving membrane phospholipids, resulting in lysis of the host...
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| Publicado no: | J Bacteriol |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society for Microbiology
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351748/ https://ncbi.nlm.nih.gov/pubmed/30455285 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JB.00623-18 |
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