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Identification of a ubiquitin-binding interface using Rosetta and DEER
ExoU is a type III-secreted cytotoxin expressing A(2) phospholipase activity when injected into eukaryotic target cells by the bacterium Pseudomonas aeruginosa. The enzymatic activity of ExoU is undetectable in vitro unless ubiquitin, a required cofactor, is added to the reaction. The role of ubiqui...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Main Authors: | , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5776994/ https://ncbi.nlm.nih.gov/pubmed/29295930 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1716861115 |
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