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Pharmacological cholesterol depletion disturbs ciliogenesis and ciliary function in developing zebrafish
Patients with an inherited inability to synthesize sufficient amounts of cholesterol develop congenital malformations of the skull, toes, kidney and heart. As development of these structures depends on functional cilia we investigated whether cholesterol regulates ciliogenesis through inhibition of...
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| Publié dans: | Commun Biol |
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| Auteurs principaux: | , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6351647/ https://ncbi.nlm.nih.gov/pubmed/30729178 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-018-0272-7 |
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