LRP1 activation attenuates white matter injury by modulating microglial polarization through Shc1/PI3K/Akt pathway after subarachnoid hemorrhage in rats

White matter injury (WMI) is associated with motor deficits and cognitive dysfunctions in subarachnoid hemorrhage (SAH) patients. Therapeutic strategy targeting WMI would likely improve the neurological outcomes after SAH. Low-density lipoprotein receptor-related protein-1 (LRP1), a scavenger recept...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Peng, Jianhua, Pang, Jinwei, Huang, Lei, Enkhjargal, Budbazar, Zhang, Tongyu, Mo, Jun, Wu, Pei, Xu, Weilin, Zuo, Yuchun, Peng, Jun, Zuo, Gang, Chen, Ligang, Tang, Jiping, Zhang, John H., Jiang, Yong
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351270/
https://ncbi.nlm.nih.gov/pubmed/30703614
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101121
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados