Neuronal-targeted TFEB rescues dysfunction of the autophagy-lysosomal pathway and alleviates ischemic injury in permanent cerebral ischemia

Mounting attention has been focused on defects in macroautophagy/autophagy and the autophagy-lysosomal pathway (ALP) in cerebral ischemia. TFEB (transcription factor EB)-mediated induction of ALP has been recently considered as the common mechanism in ameliorating the pathological lesion of myocardi...

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Udgivet i:Autophagy
Main Authors: Liu, Yueyang, Xue, Xue, Zhang, Haotian, Che, Xiaohang, Luo, Jing, Wang, Ping, Xu, Jiaoyan, Xing, Zheng, Yuan, Linlin, Liu, Yinglu, Fu, Xiaoxiao, Su, Dongmei, Sun, Shibo, Zhang, Haonan, Wu, Chunfu, Yang, Jingyu
Format: Artigo
Sprog:Inglês
Udgivet: Taylor & Francis 2018
Fag:
Research Paper - Basic Science
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6351122/
https://ncbi.nlm.nih.gov/pubmed/30304977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15548627.2018.1531196
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