A carregar...
Lysosomal dysfunction of corneal fibroblasts underlies the pathogenesis of Granular Corneal Dystrophy Type 2 and can be rescued by TFEB
Granular corneal dystrophy type 2 (GCD2) is the most common form of transforming growth factor β‐induced (TGFBI) gene‐linked corneal dystrophy and is pathologically characterized by the corneal deposition of mutant‐TGFBIp. The defective autophagic degradation of pathogenic mutant‐TGFBIp has been sho...
Na minha lista:
| Publicado no: | J Cell Mol Med |
|---|---|
| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2020
|
| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7521267/ https://ncbi.nlm.nih.gov/pubmed/32667742 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jcmm.15646 |
| Tags: |
Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!
|