Characterization and Synthesis of Eudistidine C, a Bioactive Marine Alkaloid with an Intriguing Molecular Scaffold

An extract of Eudistoma sp. provided eudistidine C (1), a heterocyclic alkaloid with a novel molecular framework. Eudistidine C (1) is a racemic natural product composed of a tetracyclic core structure further elaborated with a p-methoxyphenyl group and a phenol-substituted aminoimidazole moiety. Th...

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Publicado no:J Org Chem
Main Authors: Chan, Susanna T. S., Nani, Roger R., Schauer, Evan A., Martin, Gary E., Williamson, R Thomas, Saurí, Josep, Buevich, Alexei V., Schafer, Wes A, Joyce, Leo A., Goey, Andrew K. L., Figg, William D., Ransom, Tanya T., Henrich, Curtis J., McKee, Tawnya C., Moser, Arvin, MacDonald, Scott A., Khan, Shabana, McMahon, James B., Schnermann, Martin J., Gustafson, Kirk R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350249/
https://ncbi.nlm.nih.gov/pubmed/27934476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.joc.6b02380
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