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Characterization by Empirical and Computational Methods of Dictyospiromide, an Intriguing Antioxidant Alkaloid from the Marine Alga Dictyota coriacea

The challenging structural motif of dictyospiromide (1), a spirosuccinimide alkaloid with antioxidant properties that are associated with activation of the Nrf2/ARE signaling pathway, was assigned using contemporary NMR experiments complemented with anisotropic NMR, chiroptical, and computational me...

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Detalhes bibliográficos
Publicado no:Org Lett
Main Authors: Yan, Pengcheng, Li, Ge, Wang, Chaojie, Wu, Jianzhang, Sun, Zhongmin, Martin, Gary E., Wang, Xiao, Reibarkh, Mikhail, Saurí, Josep, Gustafson, Kirk R.
Formato: Artigo
Idioma:Inglês
Publicado em: 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7487124/
https://ncbi.nlm.nih.gov/pubmed/31539931
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.9b02856
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