Suppression of HMGB1 Released in the Glioblastoma Tumor Microenvironment Reduces Tumoral Edema

HMGB1 is a ubiquitously expressed intracellular protein that binds DNA and transcription factors and regulates chromosomal structure and function. Under conditions of cell death or stress, it is actively or passively released by cells into the extracellular environment, where it functions as damage-...

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Udgivet i:Mol Ther Oncolytics
Main Authors: Hong, Bangxing, Muili, Kamaldeen, Bolyard, Chelsea, Russell, Luke, Lee, Tae Jin, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Yan, Yuanqing, Ballester, Leomar Y., Bockhorst, Kurt H., Kaur, Balveen
Format: Artigo
Sprog:Inglês
Udgivet: American Society of Gene & Cell Therapy 2018
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350213/
https://ncbi.nlm.nih.gov/pubmed/30719499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.11.005
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