Suppression of HMGB1 Released in the Glioblastoma Tumor Microenvironment Reduces Tumoral Edema

HMGB1 is a ubiquitously expressed intracellular protein that binds DNA and transcription factors and regulates chromosomal structure and function. Under conditions of cell death or stress, it is actively or passively released by cells into the extracellular environment, where it functions as damage-...

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Veröffentlicht in:Mol Ther Oncolytics
Hauptverfasser: Hong, Bangxing, Muili, Kamaldeen, Bolyard, Chelsea, Russell, Luke, Lee, Tae Jin, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Yan, Yuanqing, Ballester, Leomar Y., Bockhorst, Kurt H., Kaur, Balveen
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society of Gene & Cell Therapy 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6350213/
https://ncbi.nlm.nih.gov/pubmed/30719499
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.omto.2018.11.005
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