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ASF1a inhibition induces p53-dependent growth arrest and senescence of cancer cells
Anti-silencing function 1a (ASF1a) is a histone H3–H4 chaperone isoform involved in chromatin assembling and transcription regulation. Recently, ASF1a has been shown to be up-regulated in certain human malignancies and required for the expression of telomerase reverse transcriptase (TERT), a factor...
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| Pubblicato in: | Cell Death Dis |
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| Autori principali: | , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Nature Publishing Group UK
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349940/ https://ncbi.nlm.nih.gov/pubmed/30692519 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1357-z |
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