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A Guide to PIN1 Function and Mutations Across Cancers
PIN1 is a member of a family of peptidylprolyl isomerases that bind phosphoproteins and catalyze the rapid cis–trans isomerization of proline peptidyl bonds, resulting in an alteration of protein structure, function, and stability. PIN1 is overexpressed in human cancers, suggesting it promotes tumor...
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| Publicado no: | Front Pharmacol |
|---|---|
| Main Authors: | , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Frontiers Media S.A.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6349750/ https://ncbi.nlm.nih.gov/pubmed/30723410 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.01477 |
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