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CD39 MEDIATED REGULATION OF TH17-CELL EFFECTOR FUNCTION IS IMPAIRED IN JUVENILE AUTOIMMUNE LIVER DISEASE
BACKGROUND & AIMS: T-helper-type 17 (Th17) cells are involved in autoimmune tissue damage. CD39 is an ectonucleotidase that catalyzes extracellular ATP/ADP hydrolysis, culminating in the generation of immunosuppressive adenosine. Functional CD39 expression confers immunosuppressive properties up...
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| Publicado no: | J Autoimmun |
|---|---|
| Main Authors: | , , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6348153/ https://ncbi.nlm.nih.gov/pubmed/27210814 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jaut.2016.05.005 |
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