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DYSFUNCTIONAL CD39(POS) REGULATORY T CELLS AND ABERRANT CONTROL OF T HELPER TYPE 17 CELLS IN AUTOIMMUNE HEPATITIS

BACKGROUND AND AIMS: Autoimmune hepatitis (AIH) is an important cause of severe liver disease and is associated with both quantitative and qualitative regulatory T cell (Treg) impairments. We have shown that Tregs express CD39, an ectonucleotidase responsible for extracellular nucleotide hydrolysis,...

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Publicat a:Hepatology
Autors principals: Grant, Charlotte R., Liberal, Rodrigo, Holder, Beth S., Cardone, John, Ma, Yun, Robson, Simon C., Vergani, Giorgina Mieli, Vergani, Diego, Longhi, Maria Serena
Format: Artigo
Idioma:Inglês
Publicat: 2014
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6377365/
https://ncbi.nlm.nih.gov/pubmed/23787765
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/hep.26583
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