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FUS causes synaptic hyperexcitability in Drosophila dendritic arborization neurons

Mutations in the nuclear localization signal of the RNA binding protein FUS cause both Frontotemporal Dementia (FTD) and Amyotrophic Lateral Sclerosis (ALS). These mutations result in a loss of FUS from the nucleus and the formation of FUS-containing cytoplasmic aggregates in patients. To better und...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Brain Res
Egile Nagusiak: Machamer, James B., Woolums, Brian M., Fuller, Gregory, Lloyd, Thomas E.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6347466/
https://ncbi.nlm.nih.gov/pubmed/29625118
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.brainres.2018.03.037
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