Integration of summary data from GWAS and eQTL studies identified novel causal BMD genes with functional predictions

PURPOSE: Osteoporosis is a common global health problem characterized by low bone mineral density (BMD) and increased risk of fracture. Genome-wide association studies (GWAS) have identified > 100 genetic loci associated with BMD. However, the functional genes responsible for most associations re...

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Dettagli Bibliografici
Pubblicato in:Bone
Autori principali: Meng, Xiang-He, Chen, Xiang-Ding, Greenbaum, Jonathan, Zeng, Qin, You, Sheng-Lan, Xiao, Hong-Mei, Tan, Li-Jun, Deng, Hong-Wen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346739/
https://ncbi.nlm.nih.gov/pubmed/29763751
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bone.2018.05.012
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