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HPLC analysis of CSF hypocretin-1 in type 1 and 2 narcolepsy
Narcolepsy is a chronic sleep disorder caused by a loss of hypocretin (hcrt) neurons in the hypothalamus. Cerebrospinal fluid (CSF) hcrt-1 measurement has been well established as a gold standard of narcolepsy diagnosis, although some portions of narcoleptic patients show normal hcrt-1 levels. We ai...
Enregistré dans:
| Publié dans: | Sci Rep |
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| Auteurs principaux: | , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Nature Publishing Group UK
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6346108/ https://ncbi.nlm.nih.gov/pubmed/30679597 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-36942-8 |
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