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Antenatal Glucocorticoid Exposure Results in Sex-Specific and Transgenerational Changes in Prefrontal Cortex Gene Transcription that Relate to Behavioural Outcomes

Synthetic glucocorticoids (sGC) are administered to women at risk for pre-term delivery to reduce respiratory distress syndrome in the newborn. The prefrontal cortex (PFC) is important in regulating stress responses and related behaviours and expresses high levels of glucocorticoid receptors (GR). F...

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Библиографические подробности
Опубликовано в: :Sci Rep
Главные авторы: Constantinof, Andrea, Moisiadis, Vasilis G., Kostaki, Alisa, Szyf, Moshe, Matthews, Stephen G.
Формат: Artigo
Язык:Inglês
Опубликовано: Nature Publishing Group UK 2019
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346022/
https://ncbi.nlm.nih.gov/pubmed/30679753
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37088-3
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