Prenatal Synthetic Glucocorticoid Treatment Changes DNA Methylation States in Male Organ Systems: Multigenerational Effects

Prenatal synthetic glucocorticoids (sGC) are administered to pregnant women at risk of delivering preterm, approximately 10% of all pregnancies. Animal studies have demonstrated that offspring exposed to elevated glucocorticoids, either by administration of sGC or as a result of maternal stress, are...

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Главные авторы: Crudo, Ariann, Petropoulos, Sophie, Moisiadis, Vasilis G., Iqbal, Majid, Kostaki, Alisa, Machnes, Ziv, Szyf, Moshe, Matthews, Stephen G.
Формат: Artigo
Язык:Inglês
Опубликовано: Endocrine Society 2012
Предметы:
Glucocorticoids-CRH-ACTH-Adrenal
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3422463/
https://ncbi.nlm.nih.gov/pubmed/22564977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1210/en.2011-2160
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