Pomegranate activates TFEB to promote autophagy-lysosomal fitness and mitophagy

Mitochondrial dysfunction underscores aging and diseases. Mitophagy (mitochondria + autophagy) is a quality control pathway that preserves mitochondrial health by targeting damaged mitochondria for autophagic degradation. Hence, molecules or compounds that can augment mitophagy are therapeutic candi...

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Pubblicato in:Sci Rep
Autori principali: Tan, Sijie, Yu, Chye Yun, Sim, Zhi Wei, Low, Zun Siong, Lee, Brianna, See, Faith, Min, Nyo, Gautam, Archana, Chu, Justin Jang Hann, Ng, Kee Woei, Wong, Esther
Natura: Artigo
Lingua:Inglês
Pubblicazione: Nature Publishing Group UK 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6346015/
https://ncbi.nlm.nih.gov/pubmed/30679718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37400-1
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