TFEB ameliorates the impairment of the autophagy-lysosome pathway in neurons induced by doxorubicin

Doxorubicin, a commonly used chemotherapy agent, induces severe cardio- and neurotoxicity. Molecular mechanisms of cardiotoxicity have been extensively studied, but mechanisms by which doxorubicin exhibits its neurotoxic properties remain unclear. Here, we show that doxorubicin impairs neuronal auto...

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Detalhes bibliográficos
Publicado no:Aging (Albany NY)
Main Authors: Moruno Manchon, Jose Felix, Uzor, Ndidi-Ese, Kesler, Shelli R., Wefel, Jeffrey S., Townley, Debra M., Nagaraja, Archana Sidalaghatta, Pradeep, Sunila, Mangala, Lingegowda S., Sood, Anil K., Tsvetkov, Andrey S.
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5270683/
https://ncbi.nlm.nih.gov/pubmed/27992857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/aging.101144
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