IRE1α-XBP1s pathway promotes prostate cancer by activating c-MYC signaling

Activation of endoplasmic reticulum (ER) stress/the unfolded protein response (UPR) has been linked to cancer, but the molecular mechanisms are poorly understood and there is a paucity of reagents to translate this for cancer therapy. Here, we report that an IRE1α RNase-specific inhibitor, MKC8866,...

詳細記述

保存先:
書誌詳細
出版年:Nat Commun
主要な著者: Sheng, Xia, Nenseth, Hatice Zeynep, Qu, Su, Kuzu, Omer F., Frahnow, Turid, Simon, Lukas, Greene, Stephanie, Zeng, Qingping, Fazli, Ladan, Rennie, Paul S., Mills, Ian G., Danielsen, Håvard, Theis, Fabian, Patterson, John B., Jin, Yang, Saatcioglu, Fahri
フォーマット: Artigo
言語:Inglês
出版事項: Nature Publishing Group UK 2019
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345973/
https://ncbi.nlm.nih.gov/pubmed/30679434
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-08152-3
タグ: タグ追加
タグなし, このレコードへの初めてのタグを付けませんか!

類似資料