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HSPA12A targets the cytoplasmic domain and affects the trafficking of the Amyloid Precursor Protein receptor SorLA

SorLA and Sortilin are multifunctional receptors involved in endocytosis and intracellular sorting of different and unrelated ligands. SorLA has recently attracted much attention as a novel strong risk gene for Alzheimer’s disease, and much effort is currently being put into understanding the underl...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Madsen, Peder, Isaksen, Toke Jost, Siupka, Piotr, Tóth, Andrea E., Nyegaard, Mette, Gustafsen, Camilla, Nielsen, Morten S.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345817/
https://ncbi.nlm.nih.gov/pubmed/30679749
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-37336-6
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