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Intrinsic and extrinsic noise of gene expression in lineage trees
Cell-to-cell heterogeneity is driven by stochasticity in intracellular reactions and the population dynamics. While these sources are usually studied separately, we develop an agent-based framework that accounts for both factors while tracking every single cell of a growing population. Apart from th...
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| 發表在: | Sci Rep |
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| 主要作者: | |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Nature Publishing Group UK
2019
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6345792/ https://ncbi.nlm.nih.gov/pubmed/30679440 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-35927-x |
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