Polarization of Rheumatoid Macrophages by TNF Targeting Through an IL-10/STAT3 Mechanism

Macrophages contribute to the pathogenesis of rheumatoid arthritis (RA). They can display different states of activation or “polarization,” notably the so-called inflammatory “M1” and the various alternative “M2” polarizations, characterized by distinct functions. Data regarding the effects of RA an...

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Udgivet i:Front Immunol
Main Authors: Degboé, Yannick, Rauwel, Benjamin, Baron, Michel, Boyer, Jean-Frédéric, Ruyssen-Witrand, Adeline, Constantin, Arnaud, Davignon, Jean-Luc
Format: Artigo
Sprog:Inglês
Udgivet: Frontiers Media S.A. 2019
Fag:
Immunology
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345709/
https://ncbi.nlm.nih.gov/pubmed/30713533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.00003
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