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No impact of concomitant methotrexate use on serious adverse event and serious infection risk in patients with rheumatoid arthritis treated with bDMARDs: a systematic literature review and meta-analysis

OBJECTIVES: To compare the risk of serious adverse events, serious infections and death caused by methotrexate and biological disease-modifying antirheumatic drug (bDMARD) combination therapy versus a bDMARD prescribed as monotherapy in rheumatoid arthritis (RA). METHODS: A systematic literature rev...

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Detalhes bibliográficos
Publicado no:RMD Open
Main Authors: Baradat, Claire, Degboé, Yannick, Constantin, Arnaud, Cantagrel, Alain, Ruyssen-Witrand, Adeline
Formato: Artigo
Idioma:Inglês
Publicado em: BMJ Publishing Group 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5337718/
https://ncbi.nlm.nih.gov/pubmed/28270933
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/rmdopen-2016-000352
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