Rheumatoid Synovial Fluids Regulate the Immunomodulatory Potential of Adipose-Derived Mesenchymal Stem Cells Through a TNF/NF-κB-Dependent Mechanism

Introduction: Adipose-derived mesenchymal stem cells (ADSC) have been shown to have remarkable immune-modulating effects. However, their efficacy in clinical trials has yet to be fully demonstrated. This could be due to a lack of a proper inflammatory environment in vivo that primes ADSC. Here, we d...

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Pubblicato in:Front Immunol
Autori principali: Sayegh, Souraya, El Atat, Oula, Diallo, Katy, Rauwel, Benjamin, Degboé, Yannick, Cavaignac, Etienne, Constantin, Arnaud, Cantagrel, Alain, Trak-Smayra, Viviane, Alaaeddine, Nada, Davignon, Jean-Luc
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2019
Soggetti:
Immunology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6611153/
https://ncbi.nlm.nih.gov/pubmed/31316519
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fimmu.2019.01482
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