SQ1274, a novel microtubule inhibitor, inhibits ovarian and uterine cancer cell growth

OBJECTIVE. Paclitaxel, a microtubule inhibitor, is subject to tumor resistance while treating high-grade serous ovarian and uterine cancer. This study aims to directly compare the effects of SQ1274, a novel microtubule inhibitor that binds to the colchicine-binding site on tubulin, and paclitaxel in...

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Publicado en:Gynecol Oncol
Autores principales: Mills, Kathryn A., Roach, S. Tanner, Quinn, Jeanne M., Guo, Lei, Beck, Hollie M., Lomonosova, Elena, Ilivicky, Anna R., Starks, Courtney M., Lawrence, Julie A., Hagemann, Andrea R., McCourt, Carolyn, Thaker, Premal H., Powell, Matthew A., Mutch, David G., Fuh, Katherine C.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2018
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345644/
https://ncbi.nlm.nih.gov/pubmed/30190114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ygyno.2018.08.008
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