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Inhibition of the Receptor Tyrosine Kinase AXL Restores Paclitaxel Chemosensitivity in Uterine Serous Cancer

Uterine serous cancer (USC) is aggressive, and the majority of recurrent cases are chemoresistant. Because the receptor tyrosine kinase AXL promotes invasion and metastasis of USC and is implicated in chemoresistance in other cancers, we assessed the role of AXL in paclitaxel resistance in USC, dete...

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Vydáno v:Mol Cancer Ther
Hlavní autoři: Palisoul, Marguerite L., Quinn, Jeanne M., Schepers, Emily, Hagemann, Ian S., Guo, Lei, Reger, Kelsey, Hagemann, Andrea R., McCourt, Carolyn K., Thaker, Premal H., Powell, Matthew A., Mutch, David G., Fuh, Katherine C.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2017
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5716844/
https://ncbi.nlm.nih.gov/pubmed/28904132
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-17-0587
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