Therapeutic Inhibition of the Receptor Tyrosine Kinase AXL Improves Sensitivity to Platinum and Taxane in Ovarian Cancer

Ovarian cancer (OvCa), one of the deadliest malignancies in female cancer patients, is characterized by recurrence and poor response to cytotoxic chemotherapies. Fewer than 30% of patients with resistant disease will respond to additional chemotherapy treatments. This study aims to determine whether...

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Veröffentlicht in:Mol Cancer Ther
Hauptverfasser: Quinn, Jeanne M., Greenwade, Molly M., Palisoul, Marguerite L., Opara, Gregory, Massad, Katina, Guo, Lei, Zhao, Peinan, Beck-Noia, Hollie, Hagemann, Ian S., Hagemann, Andrea R., McCourt, Carolyn K., Thaker, Premal H., Powell, Matthew A., Mutch, David G., Fuh, Katherine C.
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6363844/
https://ncbi.nlm.nih.gov/pubmed/30478151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1535-7163.MCT-18-0537
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