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Cumulative mitochondrial activity correlates with ototoxin susceptibility in zebrafish mechanosensory hair cells

Mitochondria play a prominent role in mechanosensory hair cell damage and death. Although hair cells are thought to be energetically demanding cells, how mitochondria respond to these demands and how this might relate to cell death is largely unexplored. Using genetically encoded indicators, we foun...

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Detalles Bibliográficos
Publicado en:eLife
Main Authors: Pickett, Sarah B, Thomas, Eric D, Sebe, Joy Y, Linbo, Tor, Esterberg, Robert, Hailey, Dale W, Raible, David W
Formato: Artigo
Idioma:Inglês
Publicado: eLife Sciences Publications, Ltd 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345563/
https://ncbi.nlm.nih.gov/pubmed/30596476
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.38062
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