mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors

BACKGROUND: Full-length tissue factor (flTF) and alternatively spliced TF (asTF) contribute to growth and spread of pancreatic ductal adenocarcinoma. It is unknown, however, if flTF and/or asTF contribute to pathobiology of pancreatic neuroendocrine tumors (pNET). OBJECTIVE: To assess TF expression...

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書誌詳細
出版年:J Thromb Haemost
主要な著者: Lewis, Clayton S, Thomas, Hala Elnakat, Orr-Asman, Melissa, Green, Lisa C, Boody, Rachel E, Matiash, Kateryna, Karve, Aniruddha, Hisada, Yohei M., Davis, Harold W, Qi, Xiaoyang, Mercer, Carol, Lucas, Fred V, Aronow, Bruce J., Mackman, Nigel, Versteeg, Henri H, Bogdanov, Vladimir Y
フォーマット: Artigo
言語:Inglês
出版事項: 2018
主題:
Article
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345540/
https://ncbi.nlm.nih.gov/pubmed/30472780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14342
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