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mTOR kinase inhibition reduces tissue factor expression and growth of pancreatic neuroendocrine tumors

BACKGROUND: Full-length tissue factor (flTF) and alternatively spliced TF (asTF) contribute to growth and spread of pancreatic ductal adenocarcinoma. It is unknown, however, if flTF and/or asTF contribute to pathobiology of pancreatic neuroendocrine tumors (pNET). OBJECTIVE: To assess TF expression...

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Detalhes bibliográficos
Publicado no:J Thromb Haemost
Main Authors: Lewis, Clayton S, Thomas, Hala Elnakat, Orr-Asman, Melissa, Green, Lisa C, Boody, Rachel E, Matiash, Kateryna, Karve, Aniruddha, Hisada, Yohei M., Davis, Harold W, Qi, Xiaoyang, Mercer, Carol, Lucas, Fred V, Aronow, Bruce J., Mackman, Nigel, Versteeg, Henri H, Bogdanov, Vladimir Y
Formato: Artigo
Idioma:Inglês
Publicado em: 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345540/
https://ncbi.nlm.nih.gov/pubmed/30472780
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/jth.14342
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