Thioguanine-based DENV-2 NS2B/NS3 protease inhibitors: Virtual screening, synthesis, biological evaluation and molecular modelling

Dengue virus Type 2 (DENV-2) is predominant serotype causing major dengue epidemics. There are a number of studies carried out to find its effective antiviral, however to date, there is still no molecule either from peptide or small molecules released as a drug. The present study aims to identify sm...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Hariono, Maywan, Choi, Sy Bing, Roslim, Ros Fatihah, Nawi, Mohamed Sufian, Tan, Mei Lan, Kamarulzaman, Ezatul Ezleen, Mohamed, Nornisah, Yusof, Rohana, Othman, Shatrah, Abd Rahman, Noorsaadah, Othman, Rozana, Wahab, Habibah A.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345492/
https://ncbi.nlm.nih.gov/pubmed/30677071
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0210869
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