Protegrin-1 Inhibits Dengue NS2B-NS3 Serine Protease and Viral Replication in MK2 Cells

Dengue diseases have an economic as well as social burden worldwide. In this study, the antiviral activity of protegrin-1 (PG-1, RGGRLCYCRRRFCVCVGR) peptide towards dengue NS2B-NS3pro and viral replication in Rhesus monkey kidney (MK2) cells was investigated. The peptide PG-1 was synthesized by soli...

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Detalhes bibliográficos
Main Authors: Rothan, Hussin A., Abdulrahman, Ammar Y., Sasikumer, Pottayil G., Othman, Shatrah, Abd Rahman, Noorsaadah, Yusof, Rohana
Formato: Artigo
Idioma:Inglês
Publicado em: Hindawi Publishing Corporation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3470887/
https://ncbi.nlm.nih.gov/pubmed/23093838
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/251482
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