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Development of a NS2B/NS3 protease inhibition assay using AlphaScreen(®) beads for screening of anti-dengue activities

BACKGROUND: Dengue infection is an endemic infectious disease and it can lead to dengue fever, dengue hemorrhagic fever, and/or dengue shock syndromes. Dengue NS2B/NS3 protease complex is essential for viral replication and is a primary target for anti-dengue drug development. In this study, a NS2B/...

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Detalhes bibliográficos
Publicado no:Heliyon
Main Authors: Abduraman, Muhammad Asyraf, Hariono, Maywan, Yusof, Rohana, Rahman, Noorsaadah Abd, Wahab, Habibah A., Tan, Mei Lan
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6289942/
https://ncbi.nlm.nih.gov/pubmed/30560214
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.heliyon.2018.e01023
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