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Nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes with reductive decarboxylation of redox-active esters

Herein, we report a nickel-catalyzed allylic defluorinative alkylation of trifluoromethyl alkenes through reductive decarboxylation of redox-active esters. The present reaction enables the preparation of functionalized gem-difluoroalkenes with the formation of sterically hindered C(sp(3))–C(sp(3)) b...

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Detalles Bibliográficos
Publicado en:Chem Sci
Main Authors: Lu, Xi, Wang, Xiao-Xu, Gong, Tian-Jun, Pi, Jing-Jing, He, Shi-Jiang, Fu, Yao
Formato: Artigo
Idioma:Inglês
Publicado: Royal Society of Chemistry 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345349/
https://ncbi.nlm.nih.gov/pubmed/30774875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1039/c8sc04335c
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