Pyrazolo[1,5-a]pyrimidine TRPC6 Antagonists for the Treatment of Gastric Cancer

Transient receptor potential canonical 6 (TRPC6) proteins form receptor-operated Ca(2+)-permeable channels, which have been thought to bring benefit to the treatment of diseases, including cancer. However, selective antagonists for TRPC channels are rare and none of them has been tested against gast...

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Publicat a:Cancer Lett
Autors principals: Ding, Mingmin, Wang, Hongbo, Qu, Chunrong, Xu, Fuchun, Zhu, Yingmin, Lv, Guangyao, Lu, Yungang, Zhou, Qingjun, Zhou, Hui, Zeng, Xiaodong, Zhang, Jingwen, Yan, Chunhong, Lin, Jiacheng, Luo, Huai-Rong, Deng, Zixing, Xiao, Yuling, Tian, Jinbin, Zhu, Michael X., Hong, Xuechuan
Format: Artigo
Idioma:Inglês
Publicat: 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345172/
https://ncbi.nlm.nih.gov/pubmed/29859875
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.canlet.2018.05.041
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