Pyrazolopyrimidines as Potent Stimulators for Transient Receptor Potential Canonical 3/6/7 Channels

Transient receptor potential canonical 3/6/7 (TRPC3/6/7) are highly homologous receptor-operated non-selective cation channels. Despite their physiological significance, very few selective and potent agonists are available for functional examination of these channels. Using a cell-based high through...

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Detalhes bibliográficos
Publicado no:J Med Chem
Main Authors: Qu, Chunrong, Ding, Mingmin, Zhu, Yingmin, Lu, Yungang, Du, Juan, Miller, Melissa, Tian, Jinbin, Zhu, Jinmei, Xu, Jian, Wen, Meng, Er-Bu, AGA, Wang, Jule, Xiao, Yuling, Wu, Meng, McManus, Owen B., Li, Min, Wu, Jilin, Luo, Huai-Rong, Cao, Zhengyu, Shen, Bing, Wang, Hongbo, Zhu, Michael X., Hong, Xuechuan
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5720685/
https://ncbi.nlm.nih.gov/pubmed/28395140
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jmedchem.7b00304
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