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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

BACKGROUND: Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is a quick,...

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Vydáno v:Stem Cell Res Ther
Hlavní autoři: Ervin, Egle-Helene, Pook, Martin, Teino, Indrek, Kasuk, Valmar, Trei, Annika, Pooga, Margus, Maimets, Toivo
Médium: Artigo
Jazyk:Inglês
Vydáno: BioMed Central 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6345057/
https://ncbi.nlm.nih.gov/pubmed/30678718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s13287-019-1144-x
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