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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

Abstract Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is...

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Main Authors: Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets
格式: Artigo
語言:Inglês
出版: BMC 2019-01-01
叢編:Stem Cell Research & Therapy
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B2M
在線閱讀:http://link.springer.com/article/10.1186/s13287-019-1144-x
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