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Targeted gene silencing in human embryonic stem cells using cell-penetrating peptide PepFect 14

Abstract Background Human embryonic stem (hES) cells serve as an invaluable tool for research and future medicine, but their transfection often leads to unwanted side effects as the method itself may induce differentiation. On the other hand, RNA interference (RNAi)-based targeted gene silencing is...

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Detalhes bibliográficos
Main Authors: Egle-Helene Ervin, Martin Pook, Indrek Teino, Valmar Kasuk, Annika Trei, Margus Pooga, Toivo Maimets
Formato: Artigo
Idioma:Inglês
Publicado em: BMC 2019-01-01
Colecção:Stem Cell Research & Therapy
Assuntos:
B2M
Acesso em linha:http://link.springer.com/article/10.1186/s13287-019-1144-x
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